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NEW YORK AND VERMONT To submit an alert or recommendation: Contact
STATE ALERTS HORSE OWNERS OF EHV-1 OUTBREAK IN WESTERN U.S. New York State Agriculture Commissioner Darrel J. Aubertine today alerted horse owners of an outbreak of Equine Herpesvirus (EHV-1) that is traced to horses that attended the National Cutting Horse Associations (NCHA) Western National Championships in Ogden, Utah April 30 through May 8, 2011. At this time, there are no New York horses known to have been exposed to the virus at the Utah show. The Department is closely monitoring the situation in the western part of the U.S. and has been in close contact with federal animal health authorities and other states. Approximately 29 states are believed to have horses that were exposed to EHV-1 at the show. Equine Herpesvirus is commonly found in equine populations worldwide, and can cause respiratory disease, abortion and sometimes neurologic disease. While EHV-1 is highly contagious among horses, it does not pose a threat to human health. New York State Veterinarian Dr. David Smith advises horse owners concerned about EHV-1 to contact their veterinarian. In general, exposed horses should be isolated and have their temperatures monitored twice daily for at least 21 days. If an exposed horse develops a fever or other signs consistent with EHV-1 infection, diagnostic testing should be performed. Testing healthy horses is generally not recommended. As a basic biosecurity measure, all newly purchased horses or horses that return from events should be immediately isolated from other horses for at least three weeks. These horses should be monitored for signs of illness, which could include fever, cough, lack of appetite, nasal or ocular discharge, swelling around the throat or incoordination. It is recommended to take the temperature on these animals twice a day during the isolation period, and have separate equipment. If a fever is recorded, a veterinarian should be called immediately. Direct horse-to-horse contact is a common route of transmission of EHV-1, but it can be indirectly transmitted as well. This occurs when infectious materials, such as nasal secretions, are carried between infected and non-infected horses by people or objects such as buckets, grooming tools, tack, etc. Fever is one of the most common clinical signs, as well as coughing and nasal discharge. Abortions caused by EHV-1 generally occur after five months of gestation. Neurologic signs of the virus are highly variable, but affected horses may appear weak and uncoordinated. Severely affected horses may become unable to rise. The neurologic form of the disease is sometimes referred to as Equine Herpes Myeloencephalopathy (EHM). Any horse in New York that exhibits signs consistent with neurologic disease should always be considered as a potential rabies case and therefore, handled with caution.
New York did have two confirmed cases of EHV-1 in March that was linked to an incident at Cornells Equine Hospital in which an infected foal died and a gelding that was exposed and confirmed with the virus is now recovering. For more information on EHV-1, visit the American Association of Equine Practitioners website or check USDA APHIS brochure on the virus.
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PERGOLIDE CRISIS UPDATE LINK
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EHV-1( Equine Herpes Virus)
recommendations and guidelines |
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>>>>>>> CORNELL UNIVERSITY ANSWERS QUESTIONS ABOUT THE RECENT PET FOOD RECALL<<<<<<<LINK
NEW BELOW: NEW YORK LABORATORIES IDENTIFY TOXIN IN RECALLED PET FOOD Aminopterin Confirmed in Recalled Pet Food and Implicated Tissue Samples New York State Agriculture Commissioner Patrick Hooker and Cornell Universitys College of Veterinary Medicine Dean Donald F. Smith announced today that scientists at the New York State Food Laboratory identified Aminopterin as a toxin present in cat food samples from Menu Foods, the manufacturer of the many brands of dog and cat food that are currently the subject of a nationwide recall.
The Food Laboratory received the pet food samples from a toxicologist at the New York State Animal Health Diagnostic Center at Cornell University, where testing has been underway to try to identify the cause of kidney failure in dogs and cats that consumed the recalled brands of pet food. At Cornells request, the Food Laboratory tested the samples for poisons and toxins, and identified Aminopterin in the pet food samples at a level of at least 40 parts per million.
We are pleased that the expertise of our New York State Food Laboratory was able to contribute to identifying the agent that caused numerous illnesses and deaths in dogs and cats across the nation, the Commissioner said. New Yorkers can be assured that we have two of the nations leading laboratory programs in food safety and animal health working on this problem.
The Dean of the Cornell College of Veterinary Medicine Donald F. Smith concurred by saying, The close partnership between the Animal Health Diagnostic Center at Cornell University and the Department of Agriculture and Markets was key to this finding.
Aminopterin, a derivative of folic acid, can cause cancer and birth defects in humans and can cause kidney damage in dogs and cats. Aminopterin is not permitted for use in the United States. On March 16, 2007, Menu Foods initiated a recall of numerous varieties of dog and cat food that were manufactured at two of its plants in the United States between December 3, 2006 and March 6, 2007. The products are both manufactured and sold under private-label and are contract-manufactured for several national brands. Information on the specific brands of pet food subject to the recall can be found at www.menufoods.com/recall. Since the recall, Department food inspectors have contacted all of the organizations that represent retail food and pet food stores to ensure that the stores were aware of the recall and that the recalled products had been removed from store shelves in New York State. New York State is home to two laboratories that are part of federal emergency lab networks, created through the U.S. Department of Homeland Security after 9-11 to keep the nations animals and food supply safe. The New York State Food Laboratory is part of the Federal Food Emergency Response Network (FERN) and as such, is capable of running a number of unique poison/toxin tests on food, including the test that identified Aminopterin. The New York State Animal Health Diagnostic Center at Cornell University is a member of the National Animal Health Laboratory Network and thus, is uniquely qualified to investigate the causes of animal health emergencies, like the sudden deaths of dogs and cats from the recently recalled pet food. ### Jessica A. Chittenden Director of Communications NYS Department of Agriculture & Markets 10B Airline Dr., Albany, NY 12235 518-457-3136
Posted by: "Eleanor Kellon, VMD" Thu Apr 12, 2007 6:48 am (PST) Please cross-post this to every list you are on, and send to all horse owners you know. Below is the early stages of an exchange with the FDA. Bottom line situation here is that the compounded pergolide most of you rely on is, according to an FDA policy statement, illegal. The FDA cannot police every compounding pharmacy, but they can more easily target the wholesalers. The wholesalers know this. No wholesale shipments, no drug available to the compounders. The FDA has proposed two solutions which appear below. One is to convince the prior pill manufacturers to produce the drug for veterinary use. This hasn't happened yet, and if it does it will be the ONLY legal source of pergolide and your costs will more than likely go up. Second option is to have your veterinarian petition the FDA for an urgent need exemption for use of pergolide in your horse: LINK Since compounding from bulk is the only available option at the moment, they would have to grant that permission but so far are offering it only on a case by case basis. Considering the thousands of horses that are probably on it, there's a chance that if we get the ball rolling with these petitions they will quickly see the size of the need and publish an exemption that allows bulk compounding of pergolide for horses. This is a link to the process of getting an exemption for an individual horse: LINK Urge your vets to do this. Third thing is that I have sent a letter and background information to every state's Board of Pharmacy. The FDA Compliance Guidelines reference two court decisions that upheld the illegality of compounding from bulk drugs. However, a recent Federal Court decision in Texas found that it was legal. We can't wait for the courts to hash it out, but the differences of opinion do leave the door open for any individual state to make an exception. Susie Gordon found a roster of state pharmacy boards yesterday. All the e-mails work. I just put it up as a .pdf file. Anyone with a horse that needs pergolide should contact your state board and let them know. Ask your vets to do the same. If we keep the pressure on, there should be some resolution of this before supplies disappear. We need to keep the petition Kellie put up rolling too. It's the documentation of need. Kellie is adding the FDA Ombudsman and all the state pharmacy boards to her list of people that get copies of the signatures every few days. Contact your local horse groups, 4-H clubs, breed organizations - anyone you can think of. Send them to the library to sign if you have to, but keep the signatures coming. We can do this! OK, below is a mail I put up on a vets' list this morning. It has the exchange with the FDA in it, and what I wrote on that list. Eleanor
Below is a copy of the first stages of an exchange with the FDA regarding pergolide. It is important to remember that the pergolide compounded from bulk drug that most are using is actually an illegal product. The FDA does not have the manpower to police every compounding pharmacy, but they can keep track of what goes into and out of a handful of wholesale supply houses. Now that there is no longer any legal market for the drug, the supply will dry up.The first option the FDA suggested was to convince manufacturers of the pills to resume production. So far, they're not interested in doing that. Maybe with FDA intervention they will. However, in that case the only option will be the manufactured pills, likely to considerably increase the cost to owners. Their second suggestion was for individual veterinarians to petition for a medically necessary veterinary drug exemption which, if I am understanding her correctly, would need to be done on a case by case basis. This could be an agonizingly slow and laborious process but if it comes to that I wanted all of you to know there may be hoops to jump through before you can get pergolide to your clients. Since there aren't any other options, you could be granted permission to use bulk compounded pergolide - assuming your compounder could get it. I'm hoping that the sheer magnitude of the need will lead to the FDA publishing a specific exemption for compounding of pergolide from bulk sources for use in horses with PPID, although that's probably the last thing they want to do. Letters and background information have also been sent to each state's board of pharmacy, to hopefully open the door for exemptions on a state by state basis. The 1994 AMDUCA legislation permitting compounding did not specifically mention compounding from bulk drug one way or the other. The compliance guidelines are FDA policy statements, not law. They reference two court decisions that upheld the ban on compounding from bulk drug, but a recent decision in a Texas federal court ruled that veterinary compounding from bulk drug was not illegal.
Eleanor M. Kellon, V.M.D. Equine Nutritional Solutions 58 Maple Farm Road Ephrata, PA 17522
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